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2-Hydroxy-1-methylethyl methacrylate, commonly known as hydroxyethyl methacrylate (HEMA), is a versatile chemical compound widely used in the production of polymers and resins. It is a clear, colorless liquid with high solubility in water, making it suitable for various applications, including adhesives, coatings, dental materials, and biocompatible materials. HEMA is recognized for its strong adhesive properties and is often used as a reactive diluent in UV-curable coatings and inks. Additionally, it plays a role in the creation of hydrogels and the manufacturing of contact lenses and other medical devices. However, it is essential to handle and use products containing 2-hydroxy-1-methylethyl methacrylate with caution, as exposure to its uncured form can cause skin and eye irritation, asthma, and allergic dermatitis.

4664-49-7

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4664-49-7 Usage

Uses

Used in Adhesives and Coatings Industry:
2-Hydroxy-1-methylethyl methacrylate is used as a reactive diluent in the formulation of UV-curable coatings and inks, providing strong adhesive properties and enhancing the performance of these products.
Used in Dental Materials:
HEMA is used as a component in dental materials, such as dental restorative resins and adhesives, due to its biocompatibility and strong adhesive properties, which contribute to the durability and effectiveness of dental treatments.
Used in Biocompatible Materials:
2-Hydroxy-1-methylethyl methacrylate is used in the creation of hydrogels, which are biocompatible materials with applications in drug delivery, tissue engineering, and wound healing.
Used in Medical Devices Manufacturing:
HEMA is utilized in the manufacturing of contact lenses and other medical devices, owing to its biocompatibility and ability to form materials with specific properties, such as oxygen permeability and mechanical strength.
Used in Research and Development:
2-Hydroxy-1-methylethyl methacrylate is employed in research and development for the synthesis of new polymers and materials with tailored properties for various applications, including biomedical, environmental, and industrial uses.

Check Digit Verification of cas no

The CAS Registry Mumber 4664-49-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,6 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4664-49:
(6*4)+(5*6)+(4*6)+(3*4)+(2*4)+(1*9)=107
107 % 10 = 7
So 4664-49-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H12O3/c1-5(2)6(8)10-7(3,4)9/h9H,1H2,2-4H3

4664-49-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-hydroxypropan-2-yl 2-methylprop-2-enoate

1.2 Other means of identification

Product number -
Other names propylene glycol methacrylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4664-49-7 SDS

4664-49-7Downstream Products

4664-49-7Relevant academic research and scientific papers

Hydroxy functional acrylate and methacrylate monomers prepared via lipase-catalyzed transacylation reactions

Popescu, Dragos,Hoogenboom, Richard,Keul, Helmut,Moeller, Martin

experimental part, p. 80 - 89 (2010/08/20)

Candida antarctica lipase B (CAL-B, Novozyme 435) catalyzes the transacylation of methyl acrylate and methyl methacrylate with diols and triols in 2-methyl-2-butanol at 50 °C. Under the experimental conditions, up to 70 mol% of the acyl donor methyl acrylate was converted. Methyl methacrylate is the less efficient acyl donor (up to 60 mol%) due to the higher sterical hindrance in the enzymatic transacylation. Under the reaction conditions high yields of the mono-acylated products are obtained, which contain minor amounts of bis(meth)acrylates. In addition it was observed that Novozyme 435 catalyzes regioselectively the acylation of the primary hydroxyl groups. In comparison with the chemical catalyzed route no selectivity was observed for unsubstituted diols. For substituted diols more mono-acylated product was formed in the lipase-catalyzed reaction than in the chemical catalyzed reaction.

High solids acrylic coating systems

-

, (2008/06/13)

High solids acrylic coating compositions are formulated by using as a reactive diluent, a low molecular weight hydroxyl-containing acrylic polymer. These polymers are prepared at about 15°-20° C. with anionic initiator concentrations greater than about 5 mole percent.

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