466635-89-2Relevant academic research and scientific papers
Diastereoselective and enantioselective lipase-catalyzed hydrolysis of stereoisomeric 2-methylene, 5-t-butylcyclohexyl acetates
Bidjou, Chahra,Aribi-Zouioueche, Louisa,Fiaud, Jean-Claude
, p. 3025 - 3027 (2007/10/03)
cis- and trans-2-Methylene-5-t-butylcyclohexanols are obtained in high (>90%) e.e. through Rabbit Gastric Lipase (RGL)-catalyzed acylation or hydrolysis of the stereoisomeric racemic alcohols or their corresponding acetates. Since these reactions were diastereomer-selective, enantiomerically enriched cis- and trans-5-t-butyl-2-methylenecyclohexanols could also be prepared from cis/trans isomeric mixtures.
Stereoselective Synthesis of Alcohols, IV Conformational Factors Determining the Stereochemistry of the Allyl Sulfoxide/ Allyl Sulfenate-Rearrangement
Hoffmann, Reinhard W.,Gerlach, Rainer,Goldmann, Siegfried
, p. 856 - 863 (2007/10/02)
The stereochemistry of the sigmatropic rearrangement of the conformationally rigid allyl sulfoxides 5 revealed a 6.2 fold preference for axial formation of the new C-O-bond.This preference dominates the 3.1 fold preference for an exo-versus endo-tran
