466639-56-5 Usage
Uses
Used in Pharmaceutical Industry:
2,6-dichloro-3-fluoro-5-bromobenzonitrile is used as a key intermediate in the synthesis of various pharmaceuticals. Its high reactivity allows for the creation of complex organic molecules that can be used in the development of new drugs.
Used in Agrochemical Industry:
2,6-dichloro-3-fluoro-5-bromobenzonitrile is utilized as a key intermediate in the manufacturing of herbicides and insecticides. Its reactivity and properties make it suitable for the production of agricultural chemicals that help control pests and weeds in farming.
Used in Specialty Chemicals Industry:
2,6-dichloro-3-fluoro-5-bromobenzonitrile is employed in the development of dyes and pigments. Its unique properties contribute to the creation of specialty chemicals that have specific applications in various industries.
Safety Precautions:
Due to its toxic and potentially harmful properties, 2,6-dichloro-3-fluoro-5-bromobenzonitrile should be handled with care. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, should be taken when working with 2,6-dichloro-3-fluoro-5-bromobenzonitrile to minimize risks and ensure the safety of individuals involved in its production and use.
Check Digit Verification of cas no
The CAS Registry Mumber 466639-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,6,6,3 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 466639-56:
(8*4)+(7*6)+(6*6)+(5*6)+(4*3)+(3*9)+(2*5)+(1*6)=195
195 % 10 = 5
So 466639-56-5 is a valid CAS Registry Number.
466639-56-5Relevant academic research and scientific papers
A 2, 4 - dichloro -3 - cyano -5 - fluoro benzoic acid synthetic method
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Paragraph 0050-0059; 0071; 0073; 0075; 0077, (2020/05/05)
The invention discloses a synthesis method for 2,4-dichloro-3-cyan-5-fluorobenzoic acid, and belongs to the technical field of chemical synthesis. The synthesis method is characterized by comprising the following steps: (1) reacting 2,6-dichloro-3-fluorobenzamide with a bromination reagent to obtain 2,6-dichloro-3-fluo-5-brombenzamide; (2) performing dehydration reaction on 2,6-dichloro-3-fluo-5-brombenzamide under the action of a dehydrating agent to obtain 2,6-dichloro-3-fluo-5-bromobenzylcyanide; (3) under the action of an alkyl magnesium halide reagent, so as to obtain an aryl magnesium halide intermediate from 2,6-dichloro-3- fluo-5-bromobenzylcyanide, reacting the aryl magnesium halide intermediate with carbon dioxide to obtain 2,4-dichloro-3-cyan-5-fluorobenzoic acid. The synthesis route has the advantages that the raw materials are cheap and easily available, the reaction yield is high, the synthesis conditions are mild, the process safety is good, the pollution is less, and the like. The synthesis method is suitable for industrial production.
A novel and facile method for synthesis of 2,4-dichloro-3-cyano-5- fluorobenzoic acid
Chen, Zhiwei,Zheng, Lidong,Su, Weike
experimental part, p. 411 - 412 (2012/09/21)
A two-step facile process for the preparation of 2,4-dichloro-3-cyano-5- fluorobenzoic acid, starting from easily available 2,6-dichloro-3- fluorobenzonitrile, has been developed. The overall yield was 58%.
