466653-36-1Relevant academic research and scientific papers
Oxindole derivatives as inhibitors of TAK1 kinase
Lockman, Jeffrey W.,Reeder, Matthew D.,Robinson, Rosann,Ormonde, Patricia A.,Cimbora, Daniel M.,Williams, Brandi L.,Willardsen, J. Adam
scheme or table, p. 1724 - 1727 (2011/05/04)
Several series of oxindole analogues were synthesized and screened for inhibitory activity against transforming growth factor-β-activating kinase 1 (TAK1). Modifications around several regions of the lead molecules were made, with a distal hydroxyl group
