4667-68-9

Basic information

• Product Name: 3-piperidin-1-yl-1-thiophen-2-yl-propan-1-ol
• CAS NO: 4667-68-9
• Molecular Weight: 225.355
• Mol File: 4667-68-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-piperidin-1-yl-1-thiophen-2-yl-propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-piperidin-1-yl-1-thiophen-2-yl-propan-1-ol(4667-68-9)
• EPA Substance Registry System: 3-piperidin-1-yl-1-thiophen-2-yl-propan-1-ol(4667-68-9)

Safety Data

• Hazardous Substances Data: 4667-68-9(Hazardous Substances Data)

Downstream Products

• 101911-90-4 Carbonic acid phenyl ester 3-piperidin-1-yl-1-thiophen-2-yl-propyl ester; hydrochloride 

Relevant articles and documents

Aryloxyheteroarylpropylamines, their preparation and use

The present invention relates to aryloxyheteroarylpropylamines of formula I wherein, X is 2- or 3-thienyl-, furanyl or pyrrolyl, all of which are unsubstituted or optionally substituted; and, R is 3,4-methylenedioxyphenyl, aryl or heteroaryl, all of which are unsubstituted or optionally substituted; and, R1 and R2 are hydrocarbyl substituents, containing 1 to 11 carbon atoms, all of which are unsubstituted or optionally substituted; or hydrogen; or, R1 and R2 together form a 5, 6 or 7 membered ring containing at least one nitrogen atom, or optionally contains two nitrogen atoms, one or two oxygen atom(s) or one or two sulfur atom(s) or a combination thereof, which ring is unsubstituted or optionally substituted,a method of preparing the same and to pharmaceutical compositions comprising the compounds., The compounds of the invention have activity against calcium overload in brain cells, and are useful in the treatment of anoxia, traumatic injury, ischemia, migraine, epilepsy, Parkinson's disease, Alzheimer's disease and other neurodegenerative diseases.