4670-34-2

Upstream product

• 5928-35-8 7-(benzyloxy)-5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one 
• 74-88-4 methyl iodide 
• 67047-05-6 4-oxo-2-phenyl-4H-1-benzopyran-5,6,7-triyl triacetate 
• 491-67-8 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one 
• 67047-06-7 7-(benzyloxy)-4-oxo-2-phenyl-4H-1-benzopyran-5,6-diyl diacetate 

Downstream Products

• 480-11-5 oroxylin A 

Relevant academic research and scientific papers

Synthetic method of oroxylin

The invention relates to a synthetic method of oroxylin. The method disclosed by the invention comprises the following steps: carrying out acetylation reaction on 5, 6, 7-trihydroxy flavone and aceticanhydride in pyridine at room temperature; reacting an obtained acetylate with benzyl bromide or benzyl chloride in the presence of an inorganic base, and carrying out hydrolysis reaction on a product in alkaline water; and reacting with methyl iodide in the presence of an inorganic base, and finally debenzylating in the presence of concentrated sulfuric acid to obtain the target product oroxylin. The method for synthesizing oroxylin provided by the invention has the advantages of simple and feasible operation, high product purity, high reaction yield and the like, and is easier for industrial production compared with the existing method.