4672-28-0Relevant academic research and scientific papers
Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase
Szajnman, Sergio H.,Montalvetti, Andrea,Wang, Youhong,Docampo, Roberto,Rodriguez, Juan B.
, p. 3231 - 3235 (2007/10/03)
Studies on the mode of action of a series of bisphosphonates derived from fatty acids, which had previously proved to be potent inhibitors against Trypanosoma cruzi proliferation in in vitro assays, have been performed. Some of these drugs proved to be potent inhibitors against the intracellular form of the parasite, exhibiting IC50 values at the low micromolar level. As bisphosphonates are FDA clinically approved for treatment of bone resorption disorders, their potential innocuousness makes them good candidates to control tropical diseases.
Oral compositions
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, (2008/06/13)
Oral compositions providing antitartar and antigingivitis benefits containing an antitartar agent and a stannous salt.
Oral composition for calculus retardation
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, (2008/06/13)
Oral compositions, such as toothpaste, mouthwash, and the like, containing certain polyphosphonic acids and their salts which retard dental calculus formation without damaging tooth structure.
