467236-27-7

Usage

Derivative of isonicotinaldehyde

2-(benzyloxy)isonicotinaldehyde is a modified version of the isonicotinaldehyde compound, with a benzyl group attached to the oxygen atom.

Use in organic synthesis and medicinal chemistry

2-(benzyloxy)isonicotinaldehyde is used as a building block and intermediate in the preparation of various pharmaceuticals and biologically active compounds.

Antifungal and antibacterial activities

2-(benzyloxy)isonicotinaldehyde has been reported to exhibit antifungal and antibacterial properties, making it potentially useful in drug development.

Potential as an anti-inflammatory and antitumor agent

2-(benzyloxy)isonicotinaldehyde has been studied for its potential to be used as an anti-inflammatory and antitumor agent.

Applications in various fields

2-(benzyloxy)isonicotinaldehyde has a range of potential applications in fields such as pharmaceuticals and biotechnology.

Upstream product

• 156367-50-9 (2-benzyloxypyridin-4-yl)methanol 

Downstream Products

• 467236-33-5 C₁₉H₂₁NO₄ 
• 945003-48-5 4-(2-(benzyloxy)pyridin-4-yl)-2-(cyclopropylamino)-6-hydroxypyrimidine-5-carbonitrile 

Relevant academic research and scientific papers

INHIBITORS OF TNFα, PDE4 AND B-RAF, COMPOSITIONS THEREOF AND METHODS OF USE THEREWITH

Provided herein are compounds having TNFα and/or PDE4 and/or B-RAF inhibitory activity, and compositions thereof. In particular, provided herein are compounds of the formula (I) and pharmaceutically acceptable salts, solvates, hydrates, clathrates, stereoisomers, polymorphs and prodrugs thereof, wherein Ar, R1, R2, R3, R4, n and Z are as described herein. Further provided herein are methods for treating or preventing various diseases and disorders by administering to a patient one or more TNFα and/or PDE4 and/or B-RAF inhibitors. In particular, provided herein are methods for preventing or treating cancer, inflammatory disorders, cognition and memory disorders and autoimmune disorders, or one or more symptoms thereof by administering to a patient one or more TNFα and/or PDE4 and/or B-RAF inhibitors.

CARBOXYLIC ACIDS

The present invention provides a novel carboxylic acid derivative, a salt thereof or a hydrate of them which is useful as an insulin sensitizer, and a medicament comprising the derivative as the effective ingredient. More specifically, it provides a carboxylic acid compound represented by the formula (I), a salt thereof or a hydrate of them. In the formula, Ar represents a 6- to 14-membered aromatic ring group which may have at least one substituent; R1, R2, R3, R4, R5, R6, R7 and R8 are the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a C1-6 alkyl group or a C1-6 alkoxy group; X represents an oxygen atom or a methylene group; Y represents a group represented by the formula (II) or (III): (wherein Z represents a group represented by the formula (IV): (wherein R9, R10, R11 and R12 are the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a C1-6 alkyl group or a C1-6 alkoxy group)); m is 0 or 1; and n is 0 or 1.