467451-33-8Relevant academic research and scientific papers
Imidazo[2,1-b]thiazoles, imidazo[2,1-b]imidazoles and pyrrolo[1,2-c]imidazoles. Synthesis, structure and evaluation of benzodiazepine receptor binding
Kiec-Kononowicz,Mueller,Pekala,Karolak-Wojciechowska,Handzlik,Lazewska
, p. 243 - 253 (2002)
As a continuation of our studies on bicyclic heterocycles with benzodiazepine receptor affinity, derivatives with a 5:5 bicyclic skeleton, namely imidazo[2,1-b]thiazoles, imidazo[2,1-b]imidazoles and pyrrolo[1,2-c]imidazoles were prepared. The compounds p
Bicyclic imidazole-4-one derivatives: A new class of antagonists for the orphan G protein-coupled receptors GPR18 and GPR55
Rempel,Atzler,Behrenswerth,Karcz,Schoeder,Hinz,Kaleta,Thimm,Kiec-Kononowicz,Müller
, p. 632 - 649 (2014/05/06)
GPR18 and GPR55 are orphan G protein-coupled receptors (GPCRs) that interact with certain cannabinoid (CB) receptor ligands. In the present study bicyclic imidazole-4-one derivatives were discovered as new scaffolds for the development of antagonists for
Imidazo[2,1-b]thiazepines: Synthesis, structure and evaluation of benzodiazepine receptor binding
Kiec-Kononowicz, Katarzyna,Karolak-Wojciechowska, Janina,Michalak, Barbara,Pekala, Elzbieta,Schumacher, Britta,Mueller, Christa E.
, p. 205 - 218 (2007/10/03)
As a continuation of our search for new ligands acting on benzodiazepine receptors among the fused 2-thiohydantoin derivatives, a series of 5-substituted imidazo[2,1-b]thiazepines was synthesized and investigated in radioligand binding studies at the benz
