467461-40-1 Usage
Description
6-(METHYLSULFONYL)-1H-INDOLE, a chemical compound with the molecular formula C9H9NO2S, is a derivative of indole featuring a methylsulfonyl group attached to the sixth carbon atom. It is recognized for its potential applications in the synthesis of pharmaceuticals and agrochemicals, as well as its possible therapeutic effects in treating various diseases and its antioxidant and antimicrobial properties, making it a compound of interest to researchers in medicinal chemistry, biochemistry, and drug development.
Uses
Used in Pharmaceutical Industry:
6-(METHYLSULFONYL)-1H-INDOLE is used as a building block for the synthesis of various pharmaceuticals due to its potential therapeutic effects in treating diseases such as cancer, inflammation, and neurological disorders. Its incorporation into drug molecules can enhance their efficacy and selectivity.
Used in Agrochemical Industry:
6-(METHYLSULFONYL)-1H-INDOLE is utilized as a component in the development of agrochemicals, contributing to the creation of more effective and targeted pesticides or herbicides.
Used in Antioxidant Applications:
6-(METHYLSULFONYL)-1H-INDOLE is employed for its antioxidant properties, which can help in the development of products that protect against oxidative stress and related cellular damage.
Used in Antimicrobial Applications:
6-(METHYLSULFONYL)-1H-INDOLE is used for its antimicrobial properties, making it a potential candidate for the development of new antimicrobial agents to combat resistant strains of bacteria and other pathogens.
Used in Research and Development:
6-(METHYLSULFONYL)-1H-INDOLE is used as a subject of study in research for its potential applications in medicinal chemistry, biochemistry, and drug development, aiding in the discovery of new therapeutic agents and understanding of disease mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 467461-40-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,7,4,6 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 467461-40:
(8*4)+(7*6)+(6*7)+(5*4)+(4*6)+(3*1)+(2*4)+(1*0)=171
171 % 10 = 1
So 467461-40-1 is a valid CAS Registry Number.
467461-40-1Relevant articles and documents
INHIBITORS OF CYCLIN DEPENDNT KINASE 7 (CDK7)
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Paragraph 312, (2018/02/28)
The present invention provides novel compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of cyclin-dependent kinase 7 (CDK7), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.
