467469-01-8Relevant academic research and scientific papers
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity
Heeres, Jan,De Jonge, Marc R.,Koymans, Lucien M. H.,Daeyaert, Frits F. D.,Vinkers, Maarten,Van Aken, Koen J. A.,Arnold, Eddy,Das, Kalyan,Kilonda, Amuri,Hoornaert, Georges J.,Compernolle, Frans,Cegla, Marek,Azzam, Rasha A.,Andries, Koen,De Béthune, Marie-Pierre,Azijn, Hilde,Pauwels, Rudi,Lewi, Paul J.,Janssen, Paul A. J.
, p. 1910 - 1918 (2007/10/03)
A series of novel pyrazinones designed as non-nucleoside reverse transcriptase inhibitors (NNRTIs) was synthesized and their anti-HIV structure-activity relationship (SAR) was studied.
