4682-48-8

Basic information

• Product Name: CDH
• Synonyms: (Z)-N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)octadec-9-enamide;Lactosylceramide (d18:1/9Z-18:1);LACTOSYLCERAMIDE, FROM BOVINE;LACTOSYL CERAMIDES, BOVINE;CDH, Ceramide β-lactoside, Ceramide dihexoside, Ceramide-β-D-lactoside;Cerebronylsphingosylglucosidogalactoside;N-[(1S,2R,E)-1-[[(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecenyl]tetracosanamide;Ceramide β-lactoside
• CAS NO: 4682-48-8
• Molecular Formula: C53H101NO13
• Molecular Weight: 960.37
• Mol File: 4682-48-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 230-240° with sintering at 180-190°
• Boiling Point: 1001.4°C at 760 mmHg
• Flash Point: 559.4°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: −20°C
• Solubility: chloroform/methanol (9:1): 10 mg/mL, clear, faintly yellow
• Merck: 13,2823
• CAS DataBase Reference: CDH(CAS DataBase Reference)
• NIST Chemistry Reference: CDH(4682-48-8)
• EPA Substance Registry System: CDH(4682-48-8)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: FK1000000
• Hazardous Substances Data: 4682-48-8(Hazardous Substances Data)

Usage

Uses

Lactosylceramide is a sphingolipid that regulates apoptosis, proliferation and stress response. It also play a role in pathogenesis and progression of genetic and non-genetic forms of chronic kidney diseases. Lactosyceramide is also important for the functioning of many cellular processess. It is highly expressed on the plasma membrane of human neutrophils and mediates innate immune functions.

InChI:InChI=1/C48H91NO13/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(53)49-36(37(52)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)35-59-47-45(58)43(56)46(39(34-51)61-47)62-48-44(57)42(55)41(54)38(33-50)60-48/h29,31,36-39,41-48,50-52,54-58H,3-28,30,32-35H2,1-2H3,(H,49,53)/b31-29+/t36?,37?,38-,39-,41+,42+,43-,44-,45-,46+,47-,48?/m1/s1