46830-10-8Relevant academic research and scientific papers
Activating water: Efficient intramolecular general base catalysis of the hydrolysis of a phosphate triester
Kirby, Anthony J.,Medeiros, Michelle,Oliveira, Pedro S.M.,Brandao, Tiago A.S.,Nome, Faruk
, p. 8475 - 8479 (2009)
We have identified the first highly efficient intramolecular general base catalysis (IGBC) of a hydrolysis reaction, in a system where two general bases are available to assist the attack of the same nucleophilic water molecule. The suggested mechanism, a
