4684-84-8

Upstream product

• 6457-55-2 3-(Hydroxymethyl)-1-methylpyridinium iodide 

Downstream Products

• 118986-00-8 1,1-dimethyl-3-hydroxymethyl-1,2,5,6-tetrahydropyridinium p-toluenesulfonate 
• 128721-23-3 2-<2-(1-methyl-1,2,5,6-tetrahydro-3-pyridylmethyl)-1,3-dithian-2-yl>-1-(4-methoxyphenylsulfonyl)indole 
• 128721-35-7 3-<2-ethylthio-2-((1-phenylsulfonyl)-2-indolyl)ethyl>-1-methyl-1,2,5,6-tetrahydropyridine 
• 13208-31-6 N_.N'-Di-(m-chlor-phenyl)-harnstoff 
• 1219-99-4 N,N'-bis(4-chlorophenyl)urea 

Relevant academic research and scientific papers

Synthesis of piperidine derivatives by reduction of pyridinium salts

Piperidine derivatives 1a-e and 2a-f have been prepared by the reduction of 3-and 4-substituted pyridinium salts with NaBH4 in moderate to excellent yields. The reactions regioselectively give 1,2,5,6-tetrahydropyridines, and the yields depend greatly upon the nature of substituents on the phenyl ring and on the nitrogen atom, the nature and the position of the substituents on the pyridyl ring, and the chain length between the aryloxy and the pyridyl groups. Copyright Taylor & Francis Group, LLC.

SYNTHESIS AND REACTIVITY OF 2-(1,3-DITHIAN-2-YL)INDOLES. III. INFLUENCE OF THE INDOLE PROTECTIVE N-PHENYLSULFONYL GROUP

Formation of the anion of 2-(1,3-dithian-2-yl)indoles was shown to be possible when the indole nitrogen is protected by a p-methoxyphenylsulfonyl group.In contrast to the corresponding N-phenylsulfonylindole dithiane 1, the anion of dithiane 2 reacts efficiently with electrophiles.The influence of the indole protective group on the metallation of 2-bis(ethylthio)-methyl-1-(phenylsulfonyl)indole (14) and the corresponding sulfoxide 24 with n-butyllithium is also reported.