468723-81-1

Basic information

• Product Name: 3-[4-(4-chloro-phenoxy)-but-2-ynylsulfanyl]-5,5-dimethyl-cyclohex-2-enone
• Synonyms: 3-[4-(4-chloro-phenoxy)-but-2-ynylsulfanyl]-5,5-dimethyl-cyclohex-2-enone
• CAS NO: 468723-81-1
• Molecular Weight: 334.867
• Mol File: 468723-81-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[4-(4-chloro-phenoxy)-but-2-ynylsulfanyl]-5,5-dimethyl-cyclohex-2-enone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(4-chloro-phenoxy)-but-2-ynylsulfanyl]-5,5-dimethyl-cyclohex-2-enone(468723-81-1)
• EPA Substance Registry System: 3-[4-(4-chloro-phenoxy)-but-2-ynylsulfanyl]-5,5-dimethyl-cyclohex-2-enone(468723-81-1)

Safety Data

• Hazardous Substances Data: 468723-81-1(Hazardous Substances Data)

Upstream product

• 105158-50-7 5,5-dimethyl-3-mercaptocyclohex-2-enone 
• 4200-22-0 1-(4-chlorophenyl)oxy-4-chloro-but-2-yne 

Relevant articles and documents

Studies on sulfoxide rearrangement: Synthesis of dimedone-annelated heterocycles

A number of 3-(4′-aryloxybut-2′-ynyl)thio-5,5-dimethyl cyclohex-2-enones are synthesized in 80-90% yield by phase transfer catalyzed reaction of 5,5-dimethyl-3-merca-ptocyclohex-2-enone with a number of 1-aryloxy-4-chlorobut-2-ynes. The sulfides are oxidized with 1equiv. of m-chloroperoxybenzoic acid and the resulting sulfoxides are then stirred at r.t. for 6-8h to give 2-aryloxymethyl-3-(m-chlorobenzoyloxy)-6,6-dimethyl-5,6,7-trihydro benzo(b)thiophene-4-ones in 70-80% yield.