46900-85-0Relevant academic research and scientific papers
Treatment of depression
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, (2008/06/13)
The invention relates to new compounds of formula I SPC1 and salts thereof with pharmaceutically acceptable acids, in which formula all the substituents may be hydrogen, while R1 and R2 may furthermore be a methyl group, R3 an alkyl group, an alkoxy-alkylene group, an alkylthioalkylene group, an alkylsulphoxyalkylene group or an alkylsulphonalkylene group having up to 8 carbon atoms or a benzyl group, and R4, R5 and R6 a halogen atom, an alkyl group, an alkoxy group or an alkylthio group having up to 6 carbon atoms, a benzyloxy group, --OH, --NH2, a mono- or dialkylamino group, in which the alkyl group(s) contain(s) 1 or 2 carbon atoms, --CN or --CF3, and two of the substituents R4, R5 and R6 may each represent a metanitro group or together a trimethylene group, a tetramethylene group, a methylene dioxy group, an ethylene dioxy group, a benzo group, a pyridino group, an indeno-1,2-, a 1,4-benzthiazino-2,3 group or a 1,4-benzoxthiino-2,3 group, with the exception of the HCl salt of the compound in which R5 and R6 each represent an orthochlorine atom and R 1, R2, R3 and R4 each represent hydrogen.
