4693-16-7 Usage
Description
2-5-dihydroxybutyrophenone is a phenol and ketone chemical compound characterized by the presence of two hydroxyl (OH) groups and a butyrophenone moiety. It has a molecular formula of C10H12O3 and is recognized for its potential therapeutic effects in psychiatric and neurological disorders, as well as its role as an intermediate in the synthesis of various medications.
Uses
Used in Pharmaceutical Industry:
2-5-dihydroxybutyrophenone is utilized as an intermediate in the synthesis of medications, specifically for the development of antipsychotic and antiemetic drugs. Its molecular structure and properties make it a valuable component in creating effective treatments for these conditions.
Used in Psychiatric and Neurological Treatments:
2-5-dihydroxybutyrophenone is employed as a potential therapeutic agent for the treatment of certain psychiatric and neurological disorders. Its presence in the synthesis of medications indicates its importance in addressing mental health and neurological conditions.
Used in Natural Product Research:
2-5-dihydroxybutyrophenone, being a natural product of certain plants and microorganisms, is used as a subject of biological activity research. Its potential biological activities warrant further investigation, which could lead to the discovery of new applications in medicine and pharmacology.
Overall, 2-5-dihydroxybutyrophenone holds significant applications in the medical and pharmaceutical fields, with its properties and potential effects being of interest for future research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 4693-16-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,9 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4693-16:
(6*4)+(5*6)+(4*9)+(3*3)+(2*1)+(1*6)=107
107 % 10 = 7
So 4693-16-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O3/c1-2-3-9(12)8-6-7(11)4-5-10(8)13/h4-6,11,13H,2-3H2,1H3
4693-16-7Relevant articles and documents
Half-wave potentials and in vitro cytotoxic evaluation of 3-acylated 2,5-bis(phenylamino)-1,4-benzoquinones on cancer cells
Benites, Julio,Valderrama, Jaime A.,Ramos, Maryan,Valenzuela, Maudy,Guerrero-Castilla, Angélica,Muccioli, Giulio G.,Calderon, Pedro Buc
, (2019/05/24)
A broad range of 3-acyl-2,5-bis(phenylamino)-1,4-benzoquinones were synthesized and their voltammetric values, as well as in vitro cancer cell cytotoxicities, were assessed. The members of this series were prepared from acylbenzoquinones and phenylamines, in moderate to good yields (47-74%), through a procedure involving a sequence of two in situ regioselective oxidative amination reactions. The cyclic voltammograms of the aminoquinones exhibit two one-electron reduction waves to the corresponding radical-anion and dianion, and two quasi-reversible oxidation peaks. The first and second half-wave potential values (E1/2) of the members of the series were sensitive to the push-pull electronic effects of the substituents around the benzoquinone nucleus. The in vitro cytotoxic activities of the 3-acyl-2,5-bis(phenylamino)-1,4-benzoquinones against human cancer cells (bladder and prostate) and non-tumor human embryonic kidney cells were measured using the MTT colorimetric method. The substitution of both aniline groups, by either methoxy (electron donating effect) or fluorine (electron withdrawal effect), decreased the cytotoxicity in the aminoquinones. Among the members of the unsubstituted phenylamino series, two of the 18 compounds showed interesting anti-cancer activities. A preliminary assay, looking for changes in the expression of selected genes, was performed. In this context, the two compounds increased TNF gene expression, suggesting an association with an inflammatory-like response.
Quinone Photochemistry. A General Synthesis of Acylhydroquinones
Kraus, George A.,Kirihara, Masayuki
, p. 3256 - 3257 (2007/10/02)
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