4698-39-9 Usage
General Description
(E)-Doxepin hydrochloride is a tricyclic antidepressant medication that works by affecting certain chemicals in the brain, such as serotonin and norepinephrine. It is primarily used to treat symptoms of depression and anxiety disorders. This medication is also used to treat insomnia and other sleep disorders. (E)-Doxepin hydrochloride is available as a capsule or a liquid suspension and is typically taken orally once daily in the evening. It should be taken exactly as directed by a doctor, and the dosage may need to be adjusted gradually to find the most effective and safe level for each individual. Common side effects may include drowsiness, dry mouth, and dizziness, and it may also cause potential interactions with other medications or substances, so it is important to consult with a healthcare professional before starting this medication.
Check Digit Verification of cas no
The CAS Registry Mumber 4698-39-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,9 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4698-39:
(6*4)+(5*6)+(4*9)+(3*8)+(2*3)+(1*9)=129
129 % 10 = 9
So 4698-39-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H25NO.ClH/c1-21(2,22(3)4)14-13-18-17-10-6-5-9-16(17)15-23-20-12-8-7-11-19(18)20;/h5-13H,14-15H2,1-4H3;1H/b18-13+;
4698-39-9Relevant articles and documents
Synthetic method of doxepin hydrochloride
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Paragraph 0036; 0047-0049; 0054-0055; 0060-0061; 0066-0067, (2020/12/30)
The invention discloses a synthetic method of doxepin hydrochloride. The synthetic method comprises the following steps: using N, N-dimethyl-3-chloropropylamine as an initial raw material, carrying out Grignard reaction, carrying out addition reaction on the reaction product and 6, 11-dihydrodibenzo [b, e] oxepine-11-ketone, and sequentially carrying out elimination reaction and salifying reactionto synthesize the final product. According to the method, high-purity doxepin hydrochloride can be obtained through four-step synthesis, a substitution reaction is not needed, and the yield of the prepared product is high. Compared with the existing synthesis process, the method has the advantages of few synthesis steps, simple process, short production period, low cost and the like.