4702-78-7Relevant articles and documents
Novel benzildihydrazone based Schiff bases: Syntheses, characterization, thermal properties, theoretical DFT calculations and biological activity studies
Elmac?, G?khan,Duyar, Halil,Ayd?ner, Burcu,Yahaya, Issah,Sefero?lu, Nurgül,?ahin, Ertan,?elik, Süheyla P?nar,A??k, Leyla,Sefero?lu, Zeynel
, p. 271 - 280 (2019)
A novel series of benzildihydrazone derived Schiff base compounds having electron-accepting and donor-donating appendices were synthesized. A combined experimental and theoretical analysis was conducted to elucidate all the characteristic and structural features of the synthesized molecules. The experimental characterizations were performed by using FT-IR, 1H/13C NMR, mass spectroscopic techniques, and X-ray diffraction methods. The thermal stabilities of the molecules were evaluated by thermal gravimetric analysis (TGA) and all them were found to be stable above 300 °C. To support the experimental, structural, and spectroscopic data of the dyes, the quantum chemical parameters were obtained within the density functional theory (DFT) calculations. In addition, some properties based on the HOMO and LUMO energies and the temperature dependence of some thermodynamic quantities (i.e. entropy, heat capacity, and enthalpy) were also studied. According to the antimicrobial activity evaluation results, compound 1f has been found to be potentially effective in suppressing microbial growth of bacteria with variable potency. The DNA cleavage activity of the compounds was analysed by gel electrophoresis assay. The results showed that the compounds have DNA cleaving activity.
Synthesis of new macrocyclic complexes of transition metals: Structural characterization and biological activity
Soni,Singh,Fahmi
, p. 1610 - 1617 (2017)
Condensation reaction between benzildihydrazone and pyridine 2,3-dicarboxylic acid, pyridine 3,4-dicarboxylic acid or pyridine 2,4-dicarboxylic acid in methanol led to novel Schiff base macrocyclic ligands L1, L2, and L3 respectively. Metal complexes of the type [MLCl2], [M = Co(II), Ni(II)], were synthesized by the reaction of a free macrocyclic ligand (L) with the corresponding metal salts in a 1 : 1 molar ratio. The complexes were characterized on the basis of analytical data, molar conductivity and magnetic susceptibility measurements, IR, 1H, and 13C NMR, and electronic spectral data. Those demonstrated that all the complexes had octahedral arrangement around the metal ions. The ligand and its complexes were screened for their antibacterial, antifungal and DNA cleavage activities. The studies demonstrate that the complexes possessed antimicrobial and DNA cleavage activities.
Graphene oxide (GO) or reduced graphene oxide (rGO): Efficient catalysts for one-pot metal-free synthesis of quinoxalines from 2-nitroaniline
Roy, Babli,Ghosh, Sujit,Ghosh, Pranab,Basu, Basudeb
, p. 6762 - 6767 (2016/01/30)
A straightforward one-pot preparation of library of quinoxalines from 2-nitroanilines under entirely metal-free conditions is described. Initial reduction of nitroaniline with hydrazine hydrate is efficiently catalyzed by graphene oxide (GO) or reduced graphene oxide (rGO), and further one-pot tandem reactions with 1,2-dicarbonyl compounds or with α-hydroxy ketones afford quinoxalines in excellent yields. The catalyst is recovered, characterized, and found to be recyclable for consecutive four runs examined with appreciable conversions.
