470463-35-5 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloro-3-trimethylsilanylethynyl-pyridine is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of diverse molecular entities with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-3-trimethylsilanylethynyl-pyridine is utilized as a key component in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used in Organic Synthesis:
As a reagent in organic synthesis, 2-Chloro-3-trimethylsilanylethynyl-pyridine facilitates various chemical reactions, enabling the formation of complex organic compounds. Its presence can influence reaction pathways and outcomes, making it a valuable tool in the synthesis of specialty chemicals and materials.
Used in Production of Functional Materials:
2-Chloro-3-trimethylsilanylethynyl-pyridine also serves as an intermediate in the production of functional materials, such as advanced polymers and materials with specific properties. Its incorporation can impart unique characteristics to these materials, broadening their applications in various industries, including electronics, coatings, and composites.
Safety Consideration:
Given its toxic nature, 2-Chloro-3-trimethylsilanylethynyl-pyridine should be handled with caution to prevent ingestion or inhalation. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, are essential when working with 2-CHLORO-3-TRIMETHYLSILANYLETHYNYL-PYRIDINE.
Check Digit Verification of cas no
The CAS Registry Mumber 470463-35-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,0,4,6 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 470463-35:
(8*4)+(7*7)+(6*0)+(5*4)+(4*6)+(3*3)+(2*3)+(1*5)=145
145 % 10 = 5
So 470463-35-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H12ClNSi/c1-13(2,3)8-6-9-5-4-7-12-10(9)11/h4-5,7H,1-3H3
470463-35-5Relevant academic research and scientific papers
Pd(0)-catalyzed domino C-N coupling/hydroamination/C-H arylation reactions: Efficient synthesis and photophysical properties of azaindolo[1,2-f]phenanthridines
Ngo, Thang Ngoc,Janert, Frank,Ehlers, Peter,Hoang, Do Huy,Dang, Tuan Thanh,Villinger, Alexander,Lochbrunner, Stefan,Langer, Peter
supporting information, p. 1293 - 1301 (2016/02/03)
A series of new 7- and 4-azaindolo[1,2-f]phenanthridines were synthesized by a domino Pd(0)-catalyzed reaction, which involves three sequential steps: C-N coupling, hydroamination, and intramolecular C-H arylation. The products show promising fluorescence properties with high quantum yields (12-65%).
Model reactions for the synthesis of azacorannulenes and related heteroaromatic compounds
Dix, Ina,Doll, Christian,Hopf, Henning,Jones, Peter G.
, p. 2547 - 2556 (2007/10/03)
4-(2-Ethynylphenyl)pyridine (10), 3-(2-ethynylphenyl)pyridine (11), 2-(2-trimethylsilylethynylphenyl)pyridine (26), and 3-ethynyl-2-phenylpyridine (13) were prepared from readily available pyridine precursors by standard coupling reactions. Pyrolysis of 10 at 810 °C/0.5 Torr provided benzo[f]isoquinoline (45) and the benzopentalene dimer 47. Pyrolysis of 11 (820 °C/0.5 Torr) afforded benzo[f]quinoline (50), benzo[h]i-soquinoline (52), and a mixture of isomers of 47. Pyrolysis of 13 (820 °C/0.3 Torr) provided benzo[h]quinoline (56) and the novel azulene derivative azuleno[1,2-b]pyridine (58). When 26 was desilylated by treatment with TBAF in THF/water, the unusual "dimerization" product 37 was produced; its structure was confirmed by X-ray structural analysis. The mechanisms of these transformations are discussed. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
CONDENSED HETEROAROMATIC RING SYSTEMS. VII. SYNTHESIS OF THIENOPYRIDINES, THIENOPYRIMIDINES, AND FUROPYRIDINES FROM o-SUBSTITUTED N-HETEROARYLACETYLENES
Sakamoto, Takao,Kondo, Yoshinori,Watanabe, Ryo,Yamanaka, Hiroshi
, p. 2719 - 2724 (2007/10/02)
The cross-coupling reaction of 2-chloro-3-iodo- and 4-chloro-3iodopyridines with phenylacetylene in the presence of dichlorobis(triphenylphosphine)palladium occured at the 3-position.The 3-ethynylpyridines containing an adjacent chloro group were converti
