470665-32-8Relevant academic research and scientific papers
trans-1,2-diaminocyclopentane-based catalyst for the asymmetric addition of alkyl-, aryl-, and vinyl groups to ketones
De Parrodi, Cecilia Anaya,Walsh, Patrick J.
, p. 2417 - 2420 (2004)
The catalytic asymmetric addition of ethyl-, phenyl-, and 1-hexenyl groups to ketones is reported. The new catalyst, generated from titanium wopropoxide and a bis(sulfonamide) diol ligand based on frans-1,2-diaminocyclopentane, gives good to excellent ena
New ligands and structural insights into the catalytic asymmetric addition of organozinc reagents to ketones
Huelgas, Gabriela,Larochelle, Lynne K.,Rivas, Lucrecia,Luchinina, Yekaterina,Toscano, Rubén A.,Carroll, Patrick J.,Walsh, Patrick J.,Anaya De Parrodi, Cecilia
experimental part, p. 4467 - 4474 (2011/08/04)
The catalytic asymmetric addition of alkyl groups to ketones has received considerable attention. Outlined herein is the synthesis of two new ligands based on the C2-symmetric 11,12-diamino-9,10-dihydro-9,10- ethanoanthracene. The scope of the new ligands has been evaluated in the catalytic asymmetric addition of diethylzinc to a variety of ketones. Enantioselectivities as high as 99% have been achieved. The structures of two of these ligands have been determined by X-ray crystallography and are compared with related structures. Additionally, the structure of a titanium complex bound to a bis(sulfonamide) diol ligand is reported.
A convenient method for the preparation of inverted tert-alkyl carboxylates from chiral tert-alcohols by a new type of oxidation-reduction condensation using 2,6-dimethyl-1,4-benzoquinone
Mukaiyama, Teruaki,Shintou, Taichi,Fukumoto, Kentaro
, p. 10538 - 10539 (2007/10/03)
Oxidation-reduction condensation using in situ-formed alkoxydiphenylphosphines, 2,6-dimethyl-1,4-benzoquinone, and carboxylic acids provided a new and efficient method for the preparation of inverted tert-alkyl carboxylates from various chiral tertiary al
