4707-57-7Relevant academic research and scientific papers
For removing the protecting group of the amino quinoline new method (by machine translation)
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Paragraph 0019; 0020; 0021; 0022, (2019/04/06)
For removing the protecting group of the amino quinoline new method. In order to 8 - butyryl amino quinoline compound as a raw material, 2 - iodo acyl benzoic acid as the oxidizing agent, in hexafluoro-isopropanol and water in the mixed solvent, after a step reaction to remove the 8 - butyryl amino quinoline compound the amide portion of the nitrogen atom of the quinoline group. After the reaction, by and in the, suction filtration, extraction, column chromatography or other operation, to obtain the primary acid radical can be obtained amine compound. 2 - Iodo acyl benzoic acid are cheap and easily obtained, the reaction step only one step, the reaction has the operation is simple, functional group compatibility is good, regional good selectivity, the yield of the product and the like, application prospect. (by machine translation)
SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION
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Page/Page column 139; 142, (2017/10/11)
Disclosed are small molecules against cereblon to enhance effector T cell function. Methodos of making thes molecules and methods of using them to treat various disease states are also disclosed.
Synthesis of antimicrobial N-phthaloyl-alanyl-derived amidophosphates and triazoles
Abdou, Wafaa M.,Ganoub, Neven A.,Sabry, Eman
experimental part, p. 1057 - 1064 (2010/03/01)
N-Phthaloyl-alanylazide reacts smoothly with trialkyl phosphites producing the corresponding α- aminophosphates. With dialkyl hydrogenphosphonates in the presence of benzoyl peroxide, amidophosphates were the isolated products whereas the oxoaziridin-1-yl
