4711-68-6

Basic information

• Product Name: N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide
• Synonyms: 2-Naphthalenecarboxamide-N-(4-ethoxyphenyl)-3-hydroxy;1-HYDROXY-3-NAPHTHOYL-P-ETHOXY ANILINE;4′-Ethoxy-3-hydroxy-2-naphthanilid;Cibanaphthol RPH;Naphthol AS-VL (C.I. 37559);C.I.Azioc Coupling Component 30;Dycosthol AS-VL.;Azoic CC 46
• CAS NO: 4711-68-6
• Molecular Formula: C₁₉H₁₇NO₃
• Molecular Weight: 307.34
• EINECS: 225-200-7
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 4711-68-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 217~219℃
• Boiling Point: 438.7 °C at 760 mmHg
• Flash Point: 219.1 °C
• Appearance: /
• Density: 1.273 g/cm³
• Vapor Pressure: 2.62E-08mmHg at 25°C
• Refractive Index: 1.686
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide(4711-68-6)
• EPA Substance Registry System: N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide(4711-68-6)

Safety Data

• Hazardous Substances Data: 4711-68-6(Hazardous Substances Data)

Usage

Preparation

4-Ethoxybenzenamine and 3-Hydroxy-2-naphthoic acid condensation.

Properties and Applications

brown powder, melting point for 217 ~ 219 ℃. Insoluble in water and sodium carbonate solution, stable to air. Mainly used for dyeing cotton fabric and glue, also used in the cotton fabric printing. This product to cotton affinity medium, coupled ability medium.

InChI:InChI=1/C19H17NO3/c1-2-23-16-9-7-15(8-10-16)20-19(22)17-11-13-5-3-4-6-14(13)12-18(17)21/h3-12,21H,2H2,1H3,(H,20,22)

Upstream product

• 123-30-8 4-amino-phenol 
• 156-43-4 4-Ethoxyaniline 
• 92-70-6 3-Hydroxy-2-naphthoic acid 

Downstream Products

• 62148-36-1 3-hydroxy-4-phenylazo-[2]naphthoic acid p-phenetidide 

Relevant articles and documents

Method for preparing naphthol AS series azo dye

The invention belongs to the technical field of chemical engineering, and particularly relates to a method for preparing naphthol AS series azo dye. According to the method, 2-hydroxy-3-naphthoic acid(also called 2,3-acid) and substituted aromatic amine are used as raw materials, and the naphthol AS azo dye is prepared under the catalytic action of a catalyst. In the whole reaction process, the reaction conditions are mild, no hydrogen chloride is generated, and the requirements on equipment are reduced, and therefore, the equipment investment cost is reduced. The by-product of the whole process flow is water, and no waste salt is generated, and therefore, the production process is more environmentally friendly, and the process of new and old kinetic energy conversion in China is promoted. The product purity is high and can reach 99% or above; and the product is light in color, is off-white, off-yellow or slightly red, and is high in quality.

Antimycobacterial N-alkoxyphenylhydroxynaphthalenecarboxamides affecting photosystem II

N-(Alkoxyphenyl)-2-hydroxynaphthalene-1-carboxamides (series A) and N-(alkoxyphenyl)-1-hydroxynaphthalene-2-carboxamides (series B) affecting photosystem (PS) II inhibited photosynthetic electron transport (PET) in spinach chloroplasts. Their inhibitory activity depended on the compound lipophilicity as well as on the position of the alkoxy substituent. The most potent PET inhibitors were 2-hydroxy-N-phenylnaphthalene-1-carboxamide and N-[3-(but-2-yloxy)phenyl]-2-hydroxynaphthalene-1-carboxamide within series A (IC50?=?28.9 and 42.5?μM, respectively) and 1-hydroxy-N-(3-propoxyphenyl)naphthalene-2-carboxamide and 1-hydroxy-N-(3-ethoxyphenyl)-naphthalene-2-carboxamide (IC50?=?2.0 and 3.1?μM, respectively) within series B. The inhibitory activity of C′(3) or C′(4) alkoxy substituted compounds of series B was considerably higher than that of C′(2) ones within series A. The PET-inhibiting activities of both series were compared with the PET inhibition of isomeric N-alkoxyphenyl-3-hydroxynaphthalene-2-carboxamides (series C) reported recently. Interactions of the studied compounds with chlorophyll a and aromatic amino acids present in pigment–protein complexes mainly in PS II were documented by fluorescence spectroscopy. The section between P680 and plastoquinone QB in the PET chain occurring on the acceptor side of PS?II can be suggested as the site of action of the compounds.