471248-31-4Relevant academic research and scientific papers
Dioxygenase-catalyzed cis-dihydroxylation of pyridine-ring systems
Boyd, Derek R.,Sharma, Narain D.,Modyanova, Ludmila V.,Carroll, Jonathan G.,Malone, John F.,Allen, Christopher C.R.,Hamilton, John T.G.,Gibson, David T.,Parales, Rebecca E.,Dalton, Howard
, p. 589 - 600 (2007/10/03)
Toluene dioxygenase-catalyzed dihydroxylation, in the carbocyclic rings of quinoline, 2-chloroquinoline, 2-methoxyquinoline, and 3-bromoquinoline, was found to yield the corresponding enantiopure cis-5,6- and -7,8-dihydrodiol metabolites using whole cells
Dioxygenase-catalysed formation of dihydrodiol metabolites of N-methyl- 2-pyridone
Modyanova, Ludmila,Azerad, Robert
, p. 3865 - 3869 (2007/10/03)
IPTG-induced cells of a recombinant strain of Escherichia coli JM109(DE3)pDTG141 expressing naphthalene dioxygenase from Pseudomonas sp. NCIB 9816-4 oxidized specifically N-methyl-2-pyridone to give the corresponding cis-5,6-dihydro-5,6-dihydroxy derivative as a major product. A small amount of the cis-3,4-dihydro-3,4-dihydroxy isomer was simultaneously formed. (C) 2000 Elsevier Science Ltd.
