4720-64-3 Usage
Uses
Used in Pharmaceutical Industry:
4-METHYL-2-PIPERIDINONE is used as a solvent for the production of pharmaceuticals, facilitating the manufacturing process by dissolving various substances to create the desired formulations.
Used in Agrochemical Industry:
In the agrochemical sector, 4-METHYL-2-PIPERIDINONE serves as a solvent, aiding in the formulation of agricultural chemicals that are essential for crop protection and enhancement of yield.
Used in Polymer Production:
4-METHYL-2-PIPERIDINONE is utilized as a solvent in the production of polymers, contributing to the creation of a wide range of polymeric materials used across different industries.
Used as a Reagent in Organic Synthesis:
4-METHYL-2-PIPERIDINONE is employed as a reagent in organic synthesis, enabling the formation of complex organic compounds through chemical reactions.
Used as a Precursor for Chemical Production:
4-METHYL-2-PIPERIDINONE also functions as a precursor, serving as a starting material for the synthesis of other chemicals, thereby expanding its applications in the chemical industry.
Safety Considerations:
While 4-METHYL-2-PIPERIDINONE is considered to have low acute toxicity, it is essential to handle it with care due to its potential to cause irritation to the skin, eyes, and respiratory system. Appropriate safety measures, including the use of personal protective equipment, should be adopted during its handling and application to mitigate any adverse effects.
Check Digit Verification of cas no
The CAS Registry Mumber 4720-64-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,2 and 0 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4720-64:
(6*4)+(5*7)+(4*2)+(3*0)+(2*6)+(1*4)=83
83 % 10 = 3
So 4720-64-3 is a valid CAS Registry Number.
4720-64-3Relevant academic research and scientific papers
Absence of Stereoelectronic Control in Hydrolysis of Cyclic Amidines
Perrin, Charles L.,Nunez, Oswaldo
, p. 5997 - 6003 (2007/10/02)
According to Deslongchamps' theory of stereoelectronic control, preferentioal cleavage of a tetrahedral intermediate occurs when there are two lone pairs antiperiplanar to the leaving group.For reasons presented (Perrin and Arrhenius, J.Am.Chem.Soc. 1982, 104, 2839), product studies of hydrolysis of cyclic amidines can test this theory, and initial results supported it.However, those results are ambiguous, owing to a mismatch of leaving abilities.We now find that hydrolysis of three six-membered ring amidines bearing matched leaving groups produces predominantly aminoamide, the product of ring cleavage, and only 3-9percent lactam, as expected from the theory.In contrast, hydrolysis of three five- or seven-membered ring amidines produces substantial (ca. 50percent) lactam.Despite attempts to accomodate these results to the theory, it is concluded that there is no general requirement for two lone pairs antiperiplanar to the leaving group and that stereoelectronic control, even in six-membered ring amidines, contributes less than 2 kcal/mol.
