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(2-hydroxyethyl)ammonium dodecylsulphate, commonly known as CHAPS, is a zwitterionic detergent that is widely utilized in the fields of biochemistry and molecular biology. Derived from the organic compound cholic acid, CHAPS is specifically designed to solubilize proteins and lipids, making it an indispensable tool in research laboratories. Its unique structure, featuring a hydrophobic tail and a hydrophilic head, endows it with the properties of an effective surfactant. This allows CHAPS to disrupt protein-protein interactions while simultaneously stabilizing protein structures. With a relatively low critical micelle concentration and non-denaturing properties towards proteins, CHAPS is a preferred choice for protein extraction and purification processes. Furthermore, its compatibility with various analytical techniques, such as electrophoresis and mass spectrometry, adds to its versatility and importance in biochemical and molecular biology research.

4722-98-9

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4722-98-9 Usage

Uses

Used in Biochemistry and Molecular Biology Research:
CHAPS is used as a solubilizing agent for proteins and lipids due to its ability to effectively disrupt protein-protein interactions and stabilize protein structures, facilitating the study and analysis of these biomolecules.
Used in Protein Extraction and Purification Processes:
As a non-denaturing detergent with a low critical micelle concentration, CHAPS is used to maintain the integrity of proteins during extraction and purification, ensuring that their functional and structural properties are preserved.
Used in Cell Lysis and Membrane Protein Solubilization:
CHAPS is employed as a lytic agent for cells and solubilizing agent for membrane proteins, capitalizing on its capacity to disrupt lipid bilayers, which is essential for the study of membrane-associated proteins.
Used in Analytical Techniques:
Owing to its compatibility with a range of analytical methods, CHAPS is used in techniques such as electrophoresis and mass spectrometry to aid in the separation, identification, and characterization of proteins and other biomolecules.

Check Digit Verification of cas no

The CAS Registry Mumber 4722-98-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,2 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4722-98:
(6*4)+(5*7)+(4*2)+(3*2)+(2*9)+(1*8)=99
99 % 10 = 9
So 4722-98-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H26O4S.C2H7NO/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;3-1-2-4/h2-12H2,1H3,(H,13,14,15);4H,1-3H2

4722-98-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Dodecyl hydrogen sulfate - 2-aminoethanol (1:1)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Corrosion inhibitors and anti-scaling agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4722-98-9 SDS

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