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1-Naphthaleneethanol, 3,4-dihydro-, 4-methylbenzenesulfonate, also known as Napabucasin, is a chemical compound that serves as a drug intermediate in the pharmaceutical industry. It has been studied for its potential anticancer properties, particularly in inhibiting cancer stem cell growth, as well as for its anti-inflammatory and antioxidant properties. Due to its potential harmful effects if ingested, inhaled, or in contact with skin, it is important to handle this chemical with care.

4725-35-3

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4725-35-3 Usage

Uses

Used in Pharmaceutical Industry:
1-Naphthaleneethanol, 3,4-dihydro-, 4-methylbenzenesulfonate is used as a drug intermediate for its potential anticancer properties, specifically in inhibiting cancer stem cell growth. It is also being investigated for its anti-inflammatory and antioxidant properties, which may contribute to the development of new therapeutic agents.
Used in Anticancer Applications:
In the field of oncology, 1-Naphthaleneethanol, 3,4-dihydro-, 4-methylbenzenesulfonate is used as a potential anticancer agent, targeting cancer stem cells and potentially contributing to the development of novel cancer treatments.
Used in Anti-inflammatory and Antioxidant Applications:
Due to its anti-inflammatory and antioxidant properties, 1-Naphthaleneethanol, 3,4-dihydro-, 4-methylbenzenesulfonate may be utilized in the development of treatments for inflammatory and oxidative stress-related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 4725-35-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,2 and 5 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4725-35:
(6*4)+(5*7)+(4*2)+(3*5)+(2*3)+(1*5)=93
93 % 10 = 3
So 4725-35-3 is a valid CAS Registry Number.

4725-35-3Relevant academic research and scientific papers

A new and convenient synthesis of 15H-16,17-dihydrocyclopenta[a] phenanthrene derivatives

Parihar,Jaiswar,Ramana

, p. 1500 - 1504 (2007/10/03)

Methyl 2-oxocyclopentane-1-carboxylate is selectively C-alkylated with several 2-(3,4-dihydro-1-naphthalenyl)ethyl-4-methylphenylsulphonates to give the corresponding seco-steroids, which on cyclodehydration followed by degradation in 5% Pd-C has afforded

A new and convenient synthesis of 13,16-diazaestrone analogs

Parihar,Ramana

, p. 1843 - 1845 (2007/10/03)

Imidazolidine-2,4-dione was chemoselectively N-alkylated at the imidic NH with several 2-(3,4-dihydro-1-naphthalenyl)ethyl-4-methylphenylsulphonates to give the corresponding imides for the first time which on selective reduction at one of the carbonyl groups followed by cyclization in PPA gave the corresponding title compounds.

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