473000-87-2Relevant academic research and scientific papers
Cyclic phosphinamides and phosphonamides, novel series of potent matrix metalloproteinase inhibitors with antitumour activity
Sorensen, Morten Dahl,Blaehr, Lars K. A.,Christensen, Mette K.,Hoyer, Thomas,Latini, Scilla,Hjarnaa, Pernille-Julia V.,Bjoerkling, Fredrik
, p. 5461 - 5484 (2007/10/03)
The design, synthesis, and structure-activity relationship (SAR) of a series of novel nonpeptidic cyclic phosphon- and phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases MMP-1, MMP-3, and MMP-9 are presented. Based on modellin
