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5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester is a chemical compound that belongs to the class of organic compounds known as indole carboxylic acids and derivatives. It is characterized by its indole ring structure, with a chloro and fluoro substituent on the 5 and 4 positions, respectively. The ethyl ester group at the 2-carboxylic acid position enhances its solubility in organic solvents, making it advantageous for use in chemical reactions. 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester serves as a valuable intermediate in the production of various functional materials, including pharmaceuticals, agrochemicals, and other organic compounds.

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  • 473257-61-3 Structure
  • Basic information

    1. Product Name: 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester
    2. Synonyms: 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester;Ethyl 5-chloro-4-fluoro-1H-indole-2-carboxylate
    3. CAS NO:473257-61-3
    4. Molecular Formula: C11H9ClFNO2
    5. Molecular Weight: 241.6460632
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 473257-61-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester(473257-61-3)
    11. EPA Substance Registry System: 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester(473257-61-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 473257-61-3(Hazardous Substances Data)

473257-61-3 Usage

Uses

Used in Pharmaceutical Industry:
5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it suitable for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester is utilized as a building block for the creation of novel agrochemicals. Its properties allow for the design of compounds with improved pesticidal or herbicidal activities, contributing to more effective crop protection strategies.
Used in Organic Synthesis:
5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester is employed as a versatile intermediate in organic synthesis. Its reactivity and functional groups enable the formation of a wide range of organic compounds, expanding the scope of chemical research and development.
Used in Functional Material Production:
5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester is used as a precursor in the production of various functional materials. Its unique structure and properties allow for the creation of materials with specific characteristics, such as improved stability, reactivity, or selectivity, which can be applied in diverse fields, including catalysis, sensors, and advanced materials.

Check Digit Verification of cas no

The CAS Registry Mumber 473257-61-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,3,2,5 and 7 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 473257-61:
(8*4)+(7*7)+(6*3)+(5*2)+(4*5)+(3*7)+(2*6)+(1*1)=163
163 % 10 = 3
So 473257-61-3 is a valid CAS Registry Number.

473257-61-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 5-chloro-4-fluoro-1H-indole-2-carboxylate

1.2 Other means of identification

Product number -
Other names ethyl 5-chloro-4-fluoroindole-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:473257-61-3 SDS

473257-61-3Downstream Products

473257-61-3Relevant articles and documents

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

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Paragraph 00287, (2017/09/27)

The present invention provides compounds, compositions thereof, and methods of using the same.

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

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Paragraph 00265, (2017/10/06)

The present invention provides compounds, compositions thereof, and methods of using the same.

SUBSTITUTED INDOLE COMPOUND

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Page/Page column 187-188, (2010/11/24)

Disclosed is an excellent LXR modulator. A compound represented by the general formula (I): (I) wherein R1, R2, R3 and R4: H, an alkyl which may be substituted, OH, an alkoxy which may be substituted, an amino which may be substituted, a halogeno, a phenyl or the like; R5: H or an alkyl; R6: -COR8 (wherein R8: an alkoxy which may be substituted, a phenyloxy which may be substituted, an amino which may be substituted, or the like), -SO2R9 (wherein R9: an alkyl which may be substituted, a phenyl which may be substituted or a heterocyclyl which may be substituted), or an alkyl which may be substituted; R7: -X2R10 [wherein R10: -COR11 (where R11: OH, an alkoxy which may be substituted or an amino which may be substituted), -SO2R12 (where R12: an alkyl which may be substituted or amino which may be substituted), -N(R13)COR14 (where R13: H or an alkyl which may be substituted; R14: H or an alkyl which may be substituted), -N(R13)SO2R15 (where R13: as defined above; R15: an alkyl which may be substituted) or tetrazol-5-yl; and X2: a single bond or an alkylene which may be substituted]; X1: a methylene which may be substituted; Y1: a phenyl which may be substituted or a heterocyclyl which may be substituted; and Y2: an aryl which may be substituted, a heterocyclyl which may be substituted or the like], or the like.

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