473313-02-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 447454-31-1 E-1-(tert-butyldimethylsilyloxy)-3-methyl-hex-2-en-6-al 
• 106-24-1 Geraniol 
• 50-00-0 formaldehyd 
• 67858-91-7 5-methyl-hex-4-enyl triphenyl phosphonium iodide 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 80007-29-0 (E)-6-hydroxy-4-methyl-4-hexenal 
• 80873-81-0 geraniol tert-butyldimethylsilyl ether 
• 473312-90-2 (2E,6Z)-8-tert-butyldimethylsilyloxy-6-methyl-2-(4-methyl-3-pentenyl)-2,6-octadien-1-ol 
• 473313-00-7 (E)-tert-butyl((5-(3,3-dimethyloxiran-2-yl)-3-methylpent-2-en-1-yl)oxy)dimethylsilane 

Downstream Products

• 473313-03-0 (2E,6Z)-7-tert-butyldiphenylsilyloxymethyl-3,11-dimethyl-2,6,10-dodecatrien-1-ol 
• 473312-91-3 (6Z,10E)-12-bromo-6-tert-butyldiphenylsilyloxymethyl-2,10-dimethyl-2,6,10-dodecatriene 
• 473312-93-5 2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-4-[(2''E,6''Z)-7''-tert-butyldiphenylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methyl-2-cyclohexen-1-one 
• 762263-78-5 (1S,4S)-2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-4-[(2''E,6''Z)-7''-tert-butyldimethylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methyl-2-cyclohexen-1-ol 
• 762263-85-4 (1R,4R)-2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-4-[(2''E,6''Z)-7''-tert-butyldimethylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methyl-2-cyclohexen-1-ol 
• 762263-84-3 (2S,1'R,4'R)-2-[(E)-5''-hydroxy-3''-methyl-3''-pentenyl]-4-[(2'''E,6'''Z)-7'''-hydroxymethyl-3''',11'''-dimethyl-2''',6''',10'''-dodecatrienyl]-3-methyl-2-cyclohexen-1-yl 2-methoxy-2-(1-naphthyl)propionate 
• 762263-76-3 (2S,1'S,4'S)-2-[(E)-5''-hydroxy-3''-methyl-3''-pentenyl]-4-[(2'''E,6'''Z)-7'''-hydroxymethyl-3''',11'''-dimethyl-2''',6''',10'''-dodecatrienyl]-3-methyl-2-cyclohexen-1-yl 2-methoxy-2-(1-naphthyl)propionate 
• 762263-74-1 2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-6-[(2''E,6''Z)-7''-tert-butyldiphenylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methoxy-2-cyclohexen-1-one 
• 762263-77-4 (S)-2-Methoxy-2-naphthalen-1-yl-propionic acid (1S,4S)-4-[(2E,6Z)-7-(tert-butyl-dimethyl-silanyloxymethyl)-3,11-dimethyl-dodeca-2,6,10-trienyl]-2-[(E)-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-pent-3-enyl]-3-methyl-cyclohex-2-enyl ester 

Relevant academic research and scientific papers

Triterpenoid total synthesis. Synthesis and absolute configuration of mispyric acid

The first synthesis of mispyric acid (1), an inhibitor β DNA polymerase β with a novel triterpene skeleton, was achieved by starting from isoprene (2), geraniol (6) and 1,5-dimethoxy-1,4-cyclohexadiene (14). The absolute configuration of the naturally occ

Synthesis of (±)-mispyric acid, a triterpene inhibitor of DNA polymerase β isolated from Mischocarpus pyriformis

The first synthesis of (±)-mispyric acid, an inhibitor of DNA polymerase β with a novel triterpene skeleton, was achieved by starting from isoprene, geraniol and 1,5-dimethoxy-1,4-cyclohexadiene.