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1-Piperidinepropanamide, N-phenyl-, also known as N-phenyl-1-piperidinepropanamide, is an organic compound with the chemical formula C12H18N2O. It is a white crystalline solid that is soluble in water and various organic solvents. 1-Piperidinepropanamide, N-phenyl- is a derivative of piperidine, a cyclic amine, and is characterized by the presence of a phenyl group attached to the nitrogen atom of the piperidine ring. It is used in the synthesis of various pharmaceuticals and chemical intermediates, particularly in the development of drugs targeting the central nervous system. The compound's structure and properties make it a versatile building block in medicinal chemistry, allowing for the creation of a wide range of molecules with potential therapeutic applications.

4734-37-6

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4734-37-6 Usage

Type of compound

Powerful synthetic opioid

Primary uses

Pain medication and anesthesia

Mechanism of action

Potent agonist at the μ-opioid receptors in the brain and spinal cord

Notable effects

Strong analgesic (pain-relieving) properties

Potential risks

High potential for abuse and addiction, respiratory depression, and overdose

Recent issues

Responsible for a significant number of overdose deaths

Legal status

Controlled substance in many countries

Check Digit Verification of cas no

The CAS Registry Mumber 4734-37-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,3 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4734-37:
(6*4)+(5*7)+(4*3)+(3*4)+(2*3)+(1*7)=96
96 % 10 = 6
So 4734-37-6 is a valid CAS Registry Number.

4734-37-6Downstream Products

4734-37-6Relevant academic research and scientific papers

LiCl-promoted amination of β-methoxy amides (γ-lactones)

Jia, Wen-Qiang,Pan, Xian-Dao,Shen, Long-Ying,Wang, Xiao-Jian,Zeng, Bing-Lin,Zhao, Hong-Yi,Zhao, Ru

, p. 34938 - 34942 (2020/10/14)

An efficient and mild method has been developed for the amination of β-methoxy amides (γ-lactones) including natural products michelolide, costunolide and parthenolide derivatives by using lithium chloride in good yields. This reaction is applicable to a wide range of substrates with good functional group tolerance. Mechanism studies show that the reactions undergo a LiCl promoted MeOH elimination from the substrates to form the corresponding α,β-unsaturated intermediates followed by the Michael addition of amines.

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