473465-06-4

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 96-32-2 bromoacetic acid methyl ester 
• 169590-42-5 4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide 

Downstream Products

• 473465-02-0 N-(2-hydroxyethyl)4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide 
• 885313-66-6 C₂₀H₁₈F₃N₃O₄S 

Relevant academic research and scientific papers

CONJUGATES WITH ANTI-INFLAMMATORY ACTIVITY

The present invention relates to new compounds represented by Formula I: wherein M represents a macrolide subunit of the substructure VIII: L represents the chain of the substructure IX or XIII: Z represents the steroid or nonsteroidal subunit derived fro

Prodrugs of COX-2 inhibitors

A compound of Formula (I), or a pharmaceutically-acceptable salt thereof, suitable for use in the treatment of a cyclooxygenase-2 mediated disease is provided. Also provided is a pharmaceutical composition comprising a compound of Formula (I), or a pharmaceutically-acceptable salt thereof, and a method for treatment of a cyclooxygenase-2 mediated disease by administering to a subject in need thereof a therapeutically-effective amount of the pharmaceutical composition.