47352-69-2Relevant academic research and scientific papers
Homolytic substitution at phosphorus for the synthesis of alkyl and aryl phosphanes
Vaillard, Santiago E.,Mueck-Lichtenfeld, Christian,Grimme, Stefan,Studer, Armido
, p. 6533 - 6536 (2008/09/17)
(Chemical Equation Presented) A transition-metal-free radical phosphonation using Me3SnPPh2 and the less toxic Me 3SiPPh2 is reported. These readily available reagents react highly efficiently with primary and secondary alkyl radicals. Moreover, aryl radicals and tertiary alkyl radicals are phosphonated with Me 3SnPPh2 (see scheme; R = aryl, alkyl, vinyl; X = 1, Br, OC(S)imidazolyl). DFT calculations provide insights into the mechanism of the reaction.
