473529-71-4Relevant academic research and scientific papers
New entry of coupling reaction of phenacylamine derivatives with silylstannane.
Iwai, Yasumasa,Kita, Kumiko,Matsushita, Yoko,Yamauchi, Aiko,Kihara, Masaru
, p. 441 - 443 (2002)
The new coupling reaction of phenacylamines with silylstannane and lithium diisopropylamide (LDA) is reported. The treatment of a phenacylamine iodide 1 with (trimethylsilyl)tributylstannane (Me3SiSnBu3) and cesium fluoride (CsF) gave a dimerization product 2 having no iodine atom. Reaction of 1 with LDA afforded a dimerization product 3 with an iodine atom. The products 2 and 3 were separated to the meso and racemic isomers, respectively.
