473537-36-9Relevant academic research and scientific papers
Novel compounds as metabotropic glutamate receptor antagonists
-
Page/Page column 12, (2008/06/13)
The present invention relates to compounds of formula (I) wherein A, E G, J, L, M, R1, R2, and R3 are as defined in the specification and claims. The invention also relates to pharmaceutical compositions containing such compounds and methods for preparing the compounds and compositions. The compounds are metabotropic glutamate receptor antagonists and are useful for the treatment of a variety of CNS disorders.
Pyrrazolo-pyrimidine derivatives
-
Page/Page column 11, (2008/06/13)
The present invention relates to pyrrazolo-pyrimidine derivatives of formula (I): wherein R1 to R4 and A are as defined in the specification, a process for the manufacture thereof, their use for treating or preventing metabotropic glutamate receptors mediated disorders, their use for the preparation of medicaments for treating such disorders and pharmaceutical compositions containing said derivatives.
Acetylenyl-pyrazolo-pyrimidine derivatives
-
Page/Page column 23, (2008/06/13)
The present invention relates to compounds of formula (I): wherein R1 to R3, A, M, L, E, G, and J are as defined in the description and claims. The invention also relates to a process for the manufacture of such compounds, pharmaceutical compositions containing them, and methods for treating CNS disorders.
Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives
-
Page/Page column 29, (2010/11/23)
This invention is concerned with compounds of the formula wherein A, B1, B2, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
PYRRAZOLO-PYRIMIDINE DERIVATIVES
-
Page/Page column 27-28, (2010/02/15)
The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5 and p are as defined in the description and claims as well as to pharmaceutically acceptable salts thereof per se and as ph
Dihydro-benzo [b] [1,4] diazepin-2-one derivatives
-
, (2008/06/13)
This invention is a dihydro-benzo [b] [1,4] diazepin-2-one derivative of the formula wherein R1, R2, R3 and Y are as defined in the specification. The invention includes pharmaceutical compositions containing these compounds, a process for their preparation and a method of treatment or prevention of acute and/or chronic neurological disorders by administering an effective amount of the compound of formula I or a pharmaceuticall acceptable salt thereof.
