473552-24-8Relevant academic research and scientific papers
Application of optically active 1,2-diol monotosylates for synthesis of β-azido and β-amino alcohols with very high enantiomeric purity. Synthesis of enantiopure (R)-octopamine, (R)-tembamide and (R)-aegeline
Tae Cho, Byung,Kyu Kang, Sang,Hye Shin, Sung
, p. 1209 - 1217 (2002)
A very convenient and highly efficient synthesis of near enantiopure β-azido and β-amino alcohols including biologically active substances such as (R)-octopamine, (R)-tembamide and (R)-aegeline from optically active 1,2-diol monotosylates is reported.
Efficient synthesis of optically active 2-azido-1-arylethanols via oxazaboronlidine - Catalysed asymmetric borane reduction
Yadav,Reddy, P. Thirupathi,Hashim, S. Riaz
, p. 1049 - 1051 (2007/10/03)
A simple, efficient, stereo- and regio-selective method for the synthesis of optically active 2-azido-1-phenylethanols by asymmetric reduction of 2-azidoacetophenones with in situ generated, oxazaborolidine- borane complexes in THF, is described. This new method appears to be an alternative to the classical methods previously reported.
