473556-39-7Relevant academic research and scientific papers
Ligand-Controlled Regiodivergence for Catalytic Stereoselective Semireduction of Allenamides
Hajiloo Shayegan, Mojtaba,Li, Zhong-Yuan,Cui, Xin
supporting information, (2021/12/02)
Ligand-controlled regiodivergence has been developed for catalytic semireduction of allenamides with excellent chemo- and stereocontrol. This system also provides an example of catalytic regiodivergent semireduction of allenes for the first time. The divergence of the semireduction is enabled by ligand switch with the same palladium pre-catalyst under operationally simple and mild conditions. Monodentate ligand XPhos exclusively promotes selective 1,2-semireduction to afford allylic amides, while bidentate ligand BINAP completely switched the regioselectivity to 2,3-semireduction, producing (E)-enamide derivatives.
Efficient atom economic approaches towards macrocyclic crownamides via ring closure metathesis
Ibrahim, Yehia A,Behbehani, Haider,Ibrahim, Maher R
, p. 4207 - 4210 (2007/10/03)
RCM of suitable 1,ω-dienes led to efficient atom economic synthetic approaches towards azacrown ether derivatives with eight- to twenty four-membered ring sizes.
