473702-20-4Relevant academic research and scientific papers
Studies on the introduction of a photoreactive aryldiazirine group into the vitamin D skeleton
Fernandez-Gacio, Ana,Mourino, Antonio
, p. 2529 - 2534 (2007/10/03)
The synthesis of a vitamin D analog with a diazirinyl benzylidene fragment replacing the side chain shows that diazirinylarylation of the upper vitamin D unit does not prevent the use of the convergent Lythgoe-Hoffman La Roche route to photoreactive analogs of potential value for photoaffinity labeling. The key step towards the diazirinylarylated upper fragment is the simultaneous oxidation of the hydroxyl and diaziridinyl groups of intermediate 10. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
