473710-39-3Relevant articles and documents
Improved convergent synthesis of 5'-epi-analogues of muraymycin nucleoside antibiotics
Spork, Anatol P.,Koppermann, Stefan,Ducho, Christian
scheme or table, p. 2503 - 2507 (2010/01/16)
Nucleoside antibiotics represent a promising class of natural products for the development of novel antibacterial agents, with particular respect to structurally simplified analogues maintaining biological activity. There are established truncated 5-epi-d
Muraymycins, novel peptidoglycan biosynthesis inhibitors: Synthesis and SAR of their analogues
Yamashita, Ayako,Norton, Emily,Petersen, Peter J.,Rasmussen, Beth A.,Singh, Guy,Yang, Youjin,Mansour, Tarek S.,Ho, Douglas M.
, p. 3345 - 3350 (2007/10/03)
A series of Muraymycin analogues was synthesized. These analogues showed excellent antimicrobial activity against gram-positive organisms. These analogues also showed excellent inhibitory activity against the target peptidoglycan biosynthesis enzyme MraY,