473733-18-5

Usage

Uses

Used in Pharmaceutical Synthesis:
(1R)-1-(3-fluorophenyl)-2-methylpropylamine is used as a chiral building block for the synthesis of various drug molecules, leveraging its optical activity to impart desired stereochemical characteristics that are crucial for the efficacy and selectivity of the resulting pharmaceuticals.
Used in the Treatment of Neurological Disorders:
Fluorenol has been studied for its potential therapeutic applications in the treatment of neurological disorders, capitalizing on its unique structural features to target specific pathways or receptors implicated in such conditions.
Used in the Development of Novel Therapeutic Agents:
As a precursor in the development of new therapeutic agents, (1R)-1-(3-fluorophenyl)-2-methylpropylamine plays a significant role in the advancement of medicine, particularly in the discovery of innovative treatments that address unmet medical needs or offer improved patient outcomes.

InChI:InChI=1/C10H14FN/c1-7(2)10(12)8-4-3-5-9(11)6-8/h3-7,10H,12H2,1-2H3/t10-/m1/s1

Downstream Products

• 681514-63-6 C₂₁H₂₄FN₅O₄S 
• 859838-12-3 C₂₁H₂₄FN₅O₃S 

Relevant academic research and scientific papers

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.