473742-80-2Relevant academic research and scientific papers
Total synthesis of (-)- and enf-(+)-vindorosine: Tandem intramolecular -diels-alder/1,3-dipolar cycloaddition of 1,3,4-oxadiazoles
Elliott, Gregory I.,Velcicky, Juraj,Ishikawa, Hayato,Li, YongKai,Boger, Dale L.
, p. 620 - 622 (2007/10/03)
(Chemical Equation Presented) From tandem to pentacycle: The intramolecular tandem [4+2]/[3+2] cycloaddicycloaddition cascade of 1,3,4-oxadiazole (Z)-1 to give the pentacyclic skeleton 2 of (-)- and ent-(+)-vindorosine introduces all the requisite substituents and functionality in a single step by which three new rings and four C-C bonds form and all six key stereocenters are installed.
Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles
Wilkie, Gordon D.,Elliott, Gregory I.,Blagg, Brian S. J.,Wolkenberg, Scott E.,Soenen, Danielle R.,Miller, Michael M.,Pollack, Scott,Boger, Dale L.
, p. 11292 - 11294 (2007/10/03)
The scope of intramolecular Diels-Alder and a novel tandem Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles is disclosed. In the cases examined, the tandem cycloadditions construct three new rings with formation of four new C-C bonds and
