473914-78-2Relevant academic research and scientific papers
Stereoselective synthesis of substituted pyrrolidines by a domino Michael addition/carbocyclization reaction
Denes, Fabrice,Chemla, Fabrice,Normant, Jean F.
, p. 3536 - 3542 (2007/10/03)
The domino 1,4-addition/carbocyclization/functionalization reaction of Michael acceptor 3 with mixed copper/zinc reagents allows the totally diastereoselective formation of 3,4-disubstituted-3-carbomethoxypyrrolidines in a three-component one-pot sequence. ( Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002).
