473923-99-8Relevant academic research and scientific papers
Pyrazole NNRTIs 4: Selection of UK-453,061 (lersivirine) as a Development Candidate
Mowbray, Charles E.,Burt, Catherine,Corbau, Romuald,Gayton, Simon,Hawes, Michael,Perros, Manos,Tran, Isabelle,Price, David A.,Quinton, Faye J.,Selby, Matthew D.,Stupple, Paul A.,Webster, Rob,Wood, Anthony
scheme or table, p. 5857 - 5860 (2010/09/03)
We prepared three discreet cohorts of potent non-nucleoside HIV reverse transcriptase inhibitors (NNRTIs) based on the recently reported 3-cyanophenoxypyrazole lead 3. Several of these compounds displayed very promising anti-HIV activity in vitro, safety,
