474023-63-7Relevant academic research and scientific papers
Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach
Tian, Xinrong,Field, Timothy B.,Switzer, Adrian G.,Mazur, Adam W.,Ebetino, Frank H.,Wos, John A.,Berberich, Steve M.,Jayasinghe, Lalith R.,Obringer, Cindy M.,Dowty, Martin E.,Pinney, Beth B.,Farmer, Julie A.,Crossdoersen, Doreen,Sheldon, Russell J.
, p. 4745 - 4761 (2007/10/03)
The design, synthesis, and structure-activity relationships (SAR) of a series of novel proline and pyrrolidine based melanocortin receptor (MCR) agonists are described. To validate a conformationally constrained Arg-Nal dipeptide analogue strategy, we fir
