474049-65-5Relevant academic research and scientific papers
Synthesis and properties of phosphabetaine structures: III. Phosphabetaines derived from tertiary phosphines and α,β-unsaturated carboxylic acids. Synthesis, structure, and chemical properties
Galkin,Bakhtiyarova,Polezhaeva,Galkina,Cherkasov,Krivolapov,Gubaidullin,Litvinov
, p. 384 - 389 (2002)
Methods of synthesis of acylate phosphabetaines by reactions of triphenylphosphine with methacrylic, cinnamic, and p-methoxycinnamic acids are developed. The phosphabetaine form is proposed to exist in equilibrium with the (σ5-oxaphospholane form. The features of methylation of the phosphabetaines are discussed.
Carboxylate Phosphabetaines Containing Chiral Carbon Atom: Synthesis and NMR Spectroscopy Data
Bakhtiyarova, Yu. V.,Galkin, V. I.,Galkina, I. V.,Karataeva, F. Kh.,Klochkov, V. V.,Morozov, M. V.,Romanov, S. R.
, p. 1333 - 1341 (2021/08/13)
Abstract: The nucleophilic addition reactions of tertiary phosphines and unsaturated carboxylic acids have led to the formation of mono- and dicarboxylate phosphabetaines containing an asymmetric carbon atom. The data of 1D and 2D NMR spectroscopy have revealed the presence of diastereotopic geminal protons of the CH2 group adjacent to the chiral center in the obtained compounds. The values of spin-spin coupling constants of the vicinal hydrogen atoms have coincided with the dihedral angles values (X-ray diffraction analysis data). [Figure not available: see fulltext.]
