4741-91-7Relevant academic research and scientific papers
A General Regioselective Synthesis of Alcohols by Cobalt-Catalyzed Hydrogenation of Epoxides
Beller, Matthias,Junge, Kathrin,Leischner, Thomas,Li, Wu,Liu, Weiping
supporting information, p. 11321 - 11324 (2020/05/16)
A straightforward methodology for the synthesis of anti-Markovnikov-type alcohols is presented. By using a specific cobalt triphos complex in the presence of Zn(OTf)2 as an additive, the hydrogenation of epoxides proceeds with high yields and selectivities. The described protocol shows a broad substrate scope, including multi-substituted internal and terminal epoxides, as well as a good functional-group tolerance. Various natural-product derivatives, including steroids, terpenoids, and sesquiterpenoids, gave access to the corresponding alcohols in moderate-to-excellent yields.
Rhenium complex-catalyzed Meinwald rearrangement reactions of oxiranes
Umeda, Rui,Muraki, Masahito,Nakamura, Yuudai,Tanaka, Tomoyuki,Kamiguchi, Kyohei,Nishiyama, Yutaka
supporting information, p. 2393 - 2395 (2017/05/29)
The Meinwald rearrangement reaction of oxiranes to the corresponding carbonyl compounds is efficiently catalyzed by the ReBr(CO)5 complex.
Zeolite-Promoted Oxidations of 1,1-Diarylethylenes
Clennan, Edward L.,Pan, Gui-Ian
, p. 4979 - 4982 (2007/10/03)
(Equation Presented) The intrazeolite photooxygenations of four diarylethylenes have been examined. Several intermediates, including an epoxide, have been identified by comparison to independently synthesized samples. Aldehyde intermediates were shown to undergo intrazeolite Norrish type I cleavages in competition with a novel new photooxygenation/autoxidation reaction.
Oxidative double bond cleavage of α-substituted styrenes with molecular oxygen
Hayashi, Yujiro,Takeda, Mitsuhiro,Miyamoto, Yuji,Shoji, Mitsuru
, p. 414 - 415 (2007/10/03)
Oxidative cleavage of the carbon-carbon double bond of α-substituted styrene derivatives proceeds under an atmospheric pressure of molecular oxygen at the solventless conditions to afford the corresponding ketones in moderate yields with no requirement for transition metal catalysts or photo-activation.
Generation of oxiranyllithiums and oxiranyl Grignard reagents having a carbanion-destabilizing group from sulfinyloxiranes: Their property and an application to asymmetric synthesis of epoxides and alcohols
Satoh, Tsuyoshi,Kobayashi, Shigeko,Nakanishi, Shino,Horiguchi, Kyoko,Irisa, Shiro
, p. 2515 - 2528 (2007/10/03)
The first generation of oxiranyllithiums and oxiranyl Grignard reagents having a carbanion-destabilizing group (alkyl group) was realized from sulfinyloxiranes via the ligand exchange reaction of sulfoxides with tert- butyllithium or ethylmagnesium chlori
The First Example of Oxiranyllithium and Oxiranyl Grignard Reagent Having a Carbanion Destabilizing Group: Generation, Property, and Some Synthetic Uses
Satoh, Tsuyoshi,Horiguchi, Kyoko
, p. 8235 - 8238 (2007/10/02)
The first generation of destablized oxiranyllithium and oxiranyl Grignard reagent from sulfinyloxiranes with t-BuLi or EtMgCl is described.Treatment of α-methyl α,β-epoxy sulfoxide (sulfinyloxirane) with t-BuLi in THF at -100 deg C gave oxiranyllithium ha
N-ALKENYL-3-HYDROXYBENZO[B]THIOPHENE-2-CARBOXAMIDE DERIVATIVES AS DUAL CYCLOOXYGENASE AND LIPOXYGENASE INHIBITORS
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, (2008/06/13)
Method for increasing resistance to gastro-intestinal irritation, and for the treatment of pain, fever, inflammation, arthritic conditions, asthma, allergic disorders, skin diseases, cardiovascular disorders, psoriasis, inflammatory bowel disease, glaucom
N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
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, (2008/06/13)
N-Alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives have been prepared by: (1) treating a substituted 2-halobenzoate with thioacetamide followed by N-alkenylation with appropriate agents, such as aldehydes, ketones, enol ethers, epoxides, aceta
