474100-07-7

Basic information

• Product Name: 2-{(3S,5R)-4-[2-((R)-1-Butoxy-ethyl)-pyrimidin-4-yl]-3,5-dimethyl-piperazin-1-yl}-4-chloro-6-phenyl-[1,3,5]triazine
• Synonyms: 2-{(3S,5R)-4-[2-((R)-1-Butoxy-ethyl)-pyrimidin-4-yl]-3,5-dimethyl-piperazin-1-yl}-4-chloro-6-phenyl-[1,3,5]triazine
• CAS NO: 474100-07-7
• Molecular Weight: 482.028
• Mol File: 474100-07-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{(3S,5R)-4-[2-((R)-1-Butoxy-ethyl)-pyrimidin-4-yl]-3,5-dimethyl-piperazin-1-yl}-4-chloro-6-phenyl-[1,3,5]triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{(3S,5R)-4-[2-((R)-1-Butoxy-ethyl)-pyrimidin-4-yl]-3,5-dimethyl-piperazin-1-yl}-4-chloro-6-phenyl-[1,3,5]triazine(474100-07-7)
• EPA Substance Registry System: 2-{(3S,5R)-4-[2-((R)-1-Butoxy-ethyl)-pyrimidin-4-yl]-3,5-dimethyl-piperazin-1-yl}-4-chloro-6-phenyl-[1,3,5]triazine(474100-07-7)

Safety Data

• Hazardous Substances Data: 474100-07-7(Hazardous Substances Data)

Upstream product

• 1700-02-3 2,4-dichloro-6-phenyl-1,3,5-triazine 

Downstream Products

• 474100-13-5 2-{(3S,5R)-4-[2-((R)-1-Butoxy-ethyl)-pyrimidin-4-yl]-3,5-dimethyl-piperazin-1-yl}-4-phenyl-[1,3,5]triazine 

Relevant articles and documents

A sorbitol dehydrogenase inhibitor of exceptional in vivo potency with a long duration of action: 1-(R)-{4-[4-(4,6-dimethyl[1,3,5]triazin-2-yl)-2R, 6S-dimethylpiperazin-1-yl]pyrimidin-2-yl}ethanol

We report here a novel sorbitol dehydrogenase inhibitor, 16, that shows very high oral potency (50 μg/kg) in normalizing elevated fructose levels in the sciatic nerve of chronically diabetic rats and sustained duration of action (>24 h). Furthermore, 16 s