474104-27-3Relevant academic research and scientific papers
Boranes in Synthesis. 2. Asymmetric Synthesis of β-Amino Alcohols. A Facile Conversion of 2-Amino Acetophenones to the Corresponding β-Amino Alcohols in High Enantiomeric Purity
Beardsley, David A.,Fisher, Gary B.,Goralski, Christian T.,Nicholson, Lawrence W.,Singaram, Bakthan
, p. 1511 - 1514 (2007/10/02)
The asymmetric reduction of 2-amino acetophenones with Ipc2BH or Ipc2BCl at -78 deg C, yields the corresponding β-amino alcohols in good to excellent yields.Although only modest (12-45percent ee) enantiomeric excesses were obtained with Ipc2BH, 75-99perce
