474111-15-4Relevant academic research and scientific papers
An efficient and practical enantiospecific synthesis of methyl chromanone- and chroman-2-carboxylates
Kim, Dong Woon,Maqusood Alam,Lee, Young Hun,Khan, M. Naseer A.,Zhang, Yong,Lee, Yong Sup
, p. 912 - 917 (2015)
Chromanone-2-carboxylates and chroman-2-carboxylates are useful building blocks for the synthesis of a variety of bioactive compounds, such as repinotan, fidarestat, and nebivolol. An efficient and practical enantiospecific synthesis of chromanone-2-carboxylates and chroman-2-carboxylates has been accomplished using intramolecular Mitsunobu etherification of methyl (S)-2-hydroxy-4-oxo-4-(2′-hydroxy)phenylbutanoates derived from l-malic acid.
Preparation method of chromanone 2-carboxylic acid or chroman 2-carboxylic acid derivatives
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Paragraph 0291-0293, (2017/05/16)
The present invention relates to a chromanone-2-carboxylic acid derivative and a chroman-2-carboxylic acid derivative which can be used as an intermediate for effective medicinal components currently available in the market, and to preparation methods the
2,6-Substituted chroman derivatives useful as beta-3 adrenoreceptor agonists
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, (2008/06/13)
This invention relates to novel 2,6-substituted chroman derivatives which are useful in the treatment of beta-3 adrenoreceptor-mediated conditions.
