474125-91-2

Basic information

• Product Name: 3β-[(O-β-D-glucopyranosyl)(1->6)-β-D-glucopyranosyl)oxy)]-17α-hydroxy-16β-[(O-β-D-xylopyranosyl)-(1->3)-2-O-acetyl-α-L-arabinopyranosyl)oxy]cholest-5-en-22-one
• Synonyms: 3β-[(O-β-D-glucopyranosyl)(1->6)-β-D-glucopyranosyl)oxy)]-17α-hydroxy-16β-[(O-β-D-xylopyranosyl)-(1->3)-2-O-acetyl-α-L-arabinopyranosyl)oxy]cholest-5-en-22-one
• CAS NO: 474125-91-2
• Molecular Weight: 1063.2
• Mol File: 474125-91-2.mol

Chemical Properties

• CAS DataBase Reference: 3β-[(O-β-D-glucopyranosyl)(1->6)-β-D-glucopyranosyl)oxy)]-17α-hydroxy-16β-[(O-β-D-xylopyranosyl)-(1->3)-2-O-acetyl-α-L-arabinopyranosyl)oxy]cholest-5-en-22-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-[(O-β-D-glucopyranosyl)(1->6)-β-D-glucopyranosyl)oxy)]-17α-hydroxy-16β-[(O-β-D-xylopyranosyl)-(1->3)-2-O-acetyl-α-L-arabinopyranosyl)oxy]cholest-5-en-22-one(474125-91-2)
• EPA Substance Registry System: 3β-[(O-β-D-glucopyranosyl)(1->6)-β-D-glucopyranosyl)oxy)]-17α-hydroxy-16β-[(O-β-D-xylopyranosyl)-(1->3)-2-O-acetyl-α-L-arabinopyranosyl)oxy]cholest-5-en-22-one(474125-91-2)

Safety Data

• Hazardous Substances Data: 474125-91-2(Hazardous Substances Data)

Relevant articles and documents

Cholestane glycosides from the bulbs of Ornithogalum thyrsoides and their cytotoxic activity against HL-60 leukemia cells

Twelve bisdesmosidic cholestane glycosides (1-12), including nine new ones (1-9), were isolated from the bulbs of Ornithogalum thyrsoides by monitoring the cytotoxic activity on HL-60 leukemia cells. The structural assignment of the new compounds was carried out by spectroscopic analysis and the results of hydrolytic cleavage. The 3-O-monoglucosides with an aromatic acyl group at the C-16 diglycoside moiety (1, 12) were extremely cytotoxic, with respective IC50 values of 0.00016 and 0.00013 μg/mL, and the other compounds, except for 2, 5, and 8, also showed cytotoxic activity as potent as etoposide (IC50 0.30 μg/mL), used as a positive control. These cholestanes were concluded to contribute to the potent cytotoxicity of the crude O. thyrsoides bulb extract.